Harold Crick
Mustafa
Federal Wildlife Marshal Willenholly
Buddy
Frank
Ron Burgundy
Brennan Huff
Dave
Steve Butabi
Ricky Bobby
Jack Wyatt
Chazz Reinhold (uncredited)
Chazz Michael Michaels
Jackie Moon
Big Earl (uncredited)
Ted (Man with the Yellow Hat) (voice)
Phil Weston
Detective Allen Gamble
Mugatu
Hobie
George W. Bush (archive footage)
Franz Liebkind
Sky Corrigan / Jesus
Corbit
Buddy (pictured)
Tenant
Megamind (voice)
Reggie (voice)
George W. Bush
Nick Halsey
Bob Woodward
Lance DeLune
Dr. Rick Marshall
Ricky Bobby (archive footage)
Armando Alvarez
McDermott (uncredited)
Cam Brady
Damien Weebs
Kevin (uncredited)
Mattel CEO
Lord Business / President Business / The Man Upstairs
Self
Self / Alex Trebek / Marty Culp
James King
Jim
Brad Whitaker
Himself / Various Characters (archive footage)
Bob
Rondell
Maxime (voice)
Jacobim Mugatu
Troy
Self / Nancy Reagan / Various Characters
Terry McTeer
Himself
Robert Benson
Scott Johansen/The Butcher
Brad
Sherlock Holmes
Michael, Brian's Boyfriend (uncredited)
Newscaster (uncredited)
Cubby
Ad-Rock (B-Boys 2)
Gil
Darren Clark
Al
Angel
Narrator
Cord Hosenbeck
Pete Stanton
President Business / Dad
The Architect
Tom Willis
Will Ferrell
Lars Erickssong
Self (archive footage)
Present
Ted Nettters / Craig Buchanan / Alex Trebek / Various (archive footage)
Arnold Darkshner
Bum
Miami Restaurant Guy #4
Therapist
Chuck Blazer
Will
President George W. Bush (voice) (uncredited)
Evil Blue Barf Bag
The Black Knight (voice)
Self - Guest
Self - Various Characters
Bob Whitely
Deangelo Vickers
Geryon (voice)
Bob Oblong (voice)
Shane Hunter
Ashley Schaeffer
Construction Worker
Self - Cameo (uncredited)
Eric Jonrosh
Fat Greek Guy / Miles 'Chatterbox' Musket (voice)
Roald Dahl
Self / Presenter
Donald Mahanahan
Self - Host
Mamet the Moocher (voice)
Self - Presenter
Adrian
Ranger Jim
Coach Lucas (voice)
Lou Adler
Marty Markowitz
Will Ferrell as Coach Brink
President George W. Bush