Zach 'Z-Man' Garrett
Otis B. Driftwood
Bong World Patron
Darrell
Self
Himself
Quinn
Logan Burnhardt
Luke
Walace
Soldier
Dexter
Officer Ray
Caleb
Mr. Suitcase
Slater
Mayor Buckman
Federal Marshall
Luigi Largo
Ricky
Chief Dinelli
Stewart
Eddie
Host
Chop-Top
Graveyard Gus
Kozlowski
Cab Driver
Johnnie
Radio DJ (voice)
Drayton Sawyer
General Williams
Jon
The Magician
Frank
Kickstand
Abner Honeywell
Darryl
The Caller (segment "Nite Flirt")
Sheriff Depford
Director
Jasper
Maddox
Ernie Dorko
Capt. Morrison (Voice)
Sal Bernando
Prof. Duncan
William Boyd
Hugo
Quilt Face
Giger
Peter Van Hooten
Westin
John Wilson
The Devil
Pastor James
Farmer Sam
Soggy Christian
Mr. Daniels
Otis Driftwood (voice)
Charles Manson
Pastor Johnson
Dave (segment "I've Got a Crush on You")
Worker
Johnny
Gimple
Chief Murken
Mr. O'Hara
Felix
Special Voice Appearance
Jacob Sutter
Dr. William de Freis
Ari Hall
Dread
Lemmas
Dr. West (voice)
Father Mark Campbell
Man on the Hill
Grey Speckled Man
Dr. Heinrich von Strasser (segment "Werewolf Women of the SS")
Dr. Hilcott
Hank
Fisherman
Pavel (voice)
Bill Bates
Otis Driftwood
Doc
Mr. Snowfeather
Buttercup
Bruce
Steve Mccreedy
Crepitus
Deadite Captain
Special Guest Judge
Bellousinni
Mr. Kharver
Richard Crane
Detective Hollis
Nazi Dad
Governor
Garvan
Task Force Officer
Carl Tanner
David Parker Ray
Chop Top
Lemmas (archive footage)
Dr. Heinrich Von Strasser
Bartender
Rex
Bronco
Jim
Possum
General McCandles
Crazy Max
Charlie
Customer #1
Bernie (voice)
Additional Voices (voice)