Cast from The Drew Barrymore Show
Drew Barrymore
Self - Host
Ross Mathews
Self - Co-Host
Cameron Diaz
Self
Gwyneth Paltrow
Self
Ellie Kemper
Self
Danny Seo
Demi Lovato
Self
Reese Witherspoon
Self
Lucy Liu
Self
David Arquette
Self
Jason Biggs
Self
Nischelle Turner
Self
Giada De Laurentiis
Self
Adam Sandler
Self
Gabrielle Union
Self
Christian Siriano
Self
Tyra Banks
Self
Billy Porter
Self
Billy Eichner
Self
Derrick Barnes
Self
Jennifer Aniston
Self
Wayne Brady
Self
Mariska Hargitay
Self
Ali Wentworth
Self
Charlize Theron
Self
Paris Hilton
Self
José Andrés Puerta
Self
Hugh Grant
Self
Olivia Rodrigo
Self
Sophia Bush
Self
Nicole Lapin
Self
Sabrina Carpenter
Self
Carla Lalli Music
Self
Scarlett Johansson
Self
Molly Shannon
Self
Michael Vartan
Self
Billie Eilish
Self
Cedric the Entertainer
Self
Kevin Frazier
Self
Awkwafina
Self
Fat Joe
Self
Fran Drescher
Self
Benito Skinner
Self
Tiki Barber
Self
Jenny Mollen
Self
Eddie Murphy
Self
Courteney Cox
Self
Neve Campbell
Self
Kathryn Hahn
Self
Jane Levy
Self
Amy Schumer
Self
Violet Young
Self
Keanu Reeves
Self
Aubrey Plaza
Self
Chloë Grace Moretz
Self
Andra Day
Self
Erin Napier
Self
Ben Napier
Self
Ben Platt
Self
Samantha Bee
Self
Kristen Wiig
Self
Jamie Dornan
Self
Annie Mumolo
Self
Steven Spielberg
Self
David Letterman
Self
Jimmy Fallon
Self
Keith Morrison
Self
Savannah Guthrie
Self
Chelsea Handler
Self
Rita Ora
Self
Kat Dennings
Self
Garcelle Beauvais
Self
Jennifer Love Hewitt
Self
Abigail Cowen
Self
Regina Hall
Self
Lana Condor
Self
Jill Kargman
Self
Priyanka Chopra Jonas
Self
Lionel Richie
Self
Dakota Johnson
Self
Jenna Ortega
Self
Ralph Macchio
Self
Regé-Jean Page
Self
Phoebe Dynevor
Self
Suzanne Somers
Self
Jet Tila
Self
Iris Apatow
Self
John Cho
Self
Lea Michele
Self
Millie Bobby Brown
Self
Eva Longoria
Self
Damson Idris
Self
Dylan Mulvaney
Self
Lewis Howes
Self
Shania Twain
Julia Fox
Bob Odenkirk
Self - Guest
Nicole Avant
Cleo Wade
Reggie Watts
Yara Shahidi
Mikel Welch
Barbara Costello
Jane Fonda
Self
Gigi Hadid
Self - Guest
Tan France
Self - Guest
John Stamos
Theresa Caputo
Bobby Berk
Ree Drummond
Chris Appleton
